英文名称:AZD5153 6-Hydroxy-2-naphthoic acid 中文名称:AZD5153 CAS:1869912-40-2 分子式:C25H33N7O3·C11H8O3 分子量:667.75 产品说明:AZD 5153 is an orally available, bivalent inhibitor of the bromodomain and extraterminal (BET) protein BRD4 (IC50 = 5 nM). It can simultaneously bind two bromodomains in BRD4, which has been shown to increase antitumor activity in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B cell lymphoma.