放线菌素D 更生霉素

Actinomycin D 放线菌素D

Synonym ：
Actinomycin C1 Actinomycin IV Dactinomycin 放线菌素D 更生霉素

Description：
Biochem/physiol Actions：An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes.
Caution：Hygroscopic and light sensitive.

应用范围
YZRNA的合成，作用于mRNA，干扰细胞的转录过程，阻止蛋白质的合成。临床上主要用于肾母细胞瘤、睾丸肿瘤及横纹肌瘤。对霍奇金氏病、绒毛膜上皮癌、恶性葡萄胎及恶性淋巴瘤亦有一定LX。

Precautions and Disclaimer:
This product is for R&D use only, not for drug,household, or other uses. Please consult the Material Safety Data Sheet for information regarding hazards and safe handling practices.

Product Description:
biological source from Streptomyces sp.
assay:~98% (HPLC)
form:powder
color:red, powder
red to orange
mp:251-253
solubility:DMSO: 1 mg/mL
ethanol: soluble
storage temp: 2-8°C

Ordering Information：
480元/5mg 285元/2mg