CRTC1 (1B5) Antibody_CRTC1 (1B5)抗体

抗体名： CRTC1 (1B5) Antibody 抗体英文名： CRTC1 (1B5) Antibody 靶点： CRTC1 (1B5) 浓度： 见详细说明信息 应用范围： WB, IF 宿主： Mouse 供应商： Abbiotec 数量： 大量 级别： 超纯 目录编号： 253035 抗原来源： Purified recombinant fragment of human CRTC1 expressed in E. coli.<br><br> 保质期： 1-2年 适应物种： H 标记物： 见下方详细说明 克隆性： 单克隆 保存条件： Store at -20°C 形态： Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. 亚型： Mouse IgG1 免疫原： Purified recombinant fragment of human CRTC1 expressed in E. coli.<br><br> 规格： 0.1 ml

CRTC1 (1B5) Antibody产品详细介绍：

产品名称：	CRTC1 (1B5) Antibody
说明书：	【点击查看详细说明及参考图片】
货号：	253035
规格：	0.1 ml
产品描述：	MECT1 (MucoEpidermoid Carcinoma Translocated 1) is a transcriptional coactivator for CREB1. CREB1 activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1 does not appear to modulate CREB1 DNA-binding activity but enhances the interaction of CREB1 with TAF4/TAFII-130. MECT1 translocates with MAML2 (MasterMind-Like Protein 2) to yield a fusion oncogene: t(11;19) (q21;p13). This translocation occurs in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. The novel fusion product that results disrupts the Notch signaling pathway. The fusion protein consists of the N-terminus of MECT1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of MECT1 has been detected in a small number of mucoepidermoid carcinomas. MECT1 is highly expressed in adult and fetal brain. Located to specific regions such as the prefrontal cortex and cerebellum. Very low expression in other tissues such as heart, spleen, lung, skeletal muscle, salivary gland, ovary and kidney.
克隆类型：	Mouse Monoclonal Antibody
亚型：	Mouse IgG1
免疫原：	Purified recombinant fragment of human CRTC1 expressed in E. coli.
适用物种：	H
应用范围：	WB, IF
应用说明：	WB: 1:500-1:2000;IF: 1:200-1:1000;
别名：	CREB-regulated transcription coactivator 1; Mucoepidermoid carcinoma translocated protein 1; Transducer of regulated cAMP response element-binding protein 1; TORC-1; Transducer of CREB protein 1; KIAA0616; MECT1; TORC1; WAMTP1; CRTC1
形态：	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
保存条件：	Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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