现货，MK-5172，selleck，美国进口， 5-alpha-reductase YZ剂，CAS号: 1206524-85-7，目录号 S1492

MK-5172 is a novel NS3/4, a protease inhibitor for chronic HCV infection (Enzyme Ki for genotype1b, 2a, 2b and 3a at ＜0.02, 0.15, 0.02 and 0.7 nM, respectively). This agent has an attractive preclinical profile including high potency in vitro, significant liver exposure upon oral dosing, and potent inhibitory activity against viral variants that are resistant to other protease inhibitors in development. MK-5172 has also demonstrated anti-viral efficacy in a chimpanzee model of chronic HCV infection. ^{[1, 2]}

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