其他说明 |
Unit Definition | One trypsin inhibitor unit (TIU) will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1.0 μmole of N-α-benzoyl-DL-arginine p-nitroanilide (BAPNA) per min at pH 7.8 at 25 °C. |
Biochem/physiol Actions | Serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Effective concentration equimolar with protease. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or <3. |
mol wt | mol wt ~6,500 |
solubility | H2O: >10 mg/mL |
storage temp. | 2-8°C |
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TEST | SPECIFICATION |
appearance | white to off-white powder |
solubility | clear colorless solution at 5mg/ml in water |
activity | 3 to 8tiu/mg solid |
unit definition | One trypsin inhibitor unit (TIU) will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1.0 micromole of N-alpha-benzoyl-DL-arginine-p-nitroanilide (BAPNA) per minute at pH7.8 at 25degc. |
shelf life | 2 years |
document # | a1153/09/26/00/2 |