供应商:
安诺伦(北京)生物科技有限公司
克隆性:
多克隆
保存条件:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
规格:
10512-60-100 μg
研究领域:Innate Immunity, Stem Cell Research, Adaptive Immunity
来源:Armenian Hamster IgG
存储溶液:Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
参考文献:Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... & Yagita, H. (1992). CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. The Journal of experimental medicine, 176(5), 1241-1249.Qin, L., Chavin, K. D., Lin, J., Yagita, H., & Bromberg, J. S. (1994). Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival. The Journal of experimental medicine, 179(1), 341-346.Chavin, K. D., Qin, L., Lin, J., Woodward, J., Baliga, P., Kato, K., ... & Bromberg, J. S. (1994). Anti-CD48 (murine CD2 ligand) mAbs suppress cell mediated immunity in vivo. International immunology, 6(5), 701-709.
特异性:Mouse
应用:FC
官网链接:http://www.bio-gems.com/flow-cytometry/conjugated-antibodies/anti-mouse-cd48-pe.html
商品关键词:Anti-Mouse CD48 PE,10512-60-100 μg,Biogems
简单描述:The HM48-1 monoclonal antibody specifically reacts with mouse CD48, a GPI-anchored molecule in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells. The utilization of the HM48-1 antibody has been reported to prolong cardiac allografts survival in in vivo studies. The antibody blocks the interaction of CD2 and CD244, inhibits CTL priming, and blocks the binding of soluble CD2 to CD48 expressing cells.
Clone: HM48-1
Format: PE
Cell Type: T Cells, B Cells, Monocytes and Macrophages
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