富含半胱氨酸运动神经元蛋白1抗体_详细资料

产品信息 富含半胱氨酸运动神经元蛋白1抗体，应用于IHC、WB、 IF、IP、ELISA等实验，公司生产的抗体每个流程都执行严格的检测标准，保证蛋白抗原产品质量，质量稳定，实验效果明显。按理化性质和生物学功能，可将其分为IgM、IgG、IgA、IgE、IgD五类。公司产品经无数次市场验证，若出 产品编号Rs-2034R 英文名称CRIM1 中文名称富含半胱氨酸运动神经元蛋白1抗体 别名Cysteine-rich motor neuron 1 protein; CRIM-1; Cysteine-rich repeat-containing protein S52; Processed cysteine-rich motor neuron 1protein; CRIM 1; CRIM1; Cysteine rich motor neuron 1 protein; Cysteine rich repeat containing protein S52; Cysteine rich transmembrane BMP regulator 1 (chordin like); Cysteine rich transmembrane BMP regulator 1; MGC138194; Processed cysteine rich motor neuron 1 protein; S52; CRIM1_HUMAN. 说明书0.1ml 0.2ml 研究领域心血管细胞生物染色质和核信号神经生物学信号转导血管内皮细胞细胞骨架细胞外基质 抗体来源Rabbit 克隆类型Polyclonal 交叉反应Human, Mouse, Rat, 产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量110kDa 细胞定位细胞膜分泌型蛋白 性状Lyophilized or Liquid 浓度1mg/1ml 免疫原KLH conjugated synthetic peptide derived from mouse CRIM1 亚型IgG 纯化方法affinity purified by Protein A 储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 ａnd 50% Glycerol. 保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMedPubMed 产品介绍background: CRIM1 interacts with BMP4 (bone morphogenic protein 4) ａnd BMP7 ａnd modulates BMP activity by affecting their processing ａnd delivery to the cell surface. By interacting with growth factors implicated in motor neuron differentiation ａnd survival, it may play a role in CNS development. It may also play a role in capillary formation ａnd maintenance during angiogenesis. Function: May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation ａnd survival. May play a role in capillary formation ａnd maintenance during angiogenesis. Modulates BMP activity by affecting its processing ａnd delivery to the cell surface. Subcellular Location: Secreted ａnd Cell membrane. Tissue Specificity: Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver ａnd small intestine. Expressed in blood vessels (at protein level). Post-translational modifications: N-glycosylated. Similarity: Contains 4 antistasin-like domains. Contains 1 IGFBP N-terminal domain. Contains 6 VWFC domains. Gene ID: 50766 Database links: Entrez Gene: 51232 Human Entrez Gene: 50766 Mouse Omim: 606189 Human SwissProt: Q9NZV1 Human SwissProt: Q9JLL0 Mouse Unigene: 699247 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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