性 状: | 【反应特异性】Human , Mouse E-Cadherin Antibody,Rabbit Monoclonal 【克隆 ID】EP700Y 【用途】WB , IHC , ICC , IP 【抗原分子量】135/80 kDa |
质量标准: | 【产品介绍】E-Cadherin, a member of the cadherin superfamily, is implicated as a key player in different cellular processes including development, m o r phology, polarity, migration a n d tissue integrity (1-2). E-cadherin is a glycoprotein with an extracellular domain that interacts with other E-cadherin molecules on adjacent cells, thereby establishing adhesion between epithelial cells. Established as a tum o r a n d metastasis suppress o r , E-cadherin expression is frequently down-regulated o r extinguished in malignancy which strongly c o r relates with po o r prognosis (3-4). Mutations in E-cadherin are found in gastric, breast, col o r ectal, thyroid a n d ovarian cancer (5). E-Cadherin Antibody,Rabbit Monoclonal WB: 1: 50,000-200,000 IHC: 1:500 ICC: 1:500 IP: 1:50 A. Western blot analysis on MCF-7 cell lysate using anti-E-cadherin RabMAb (cat. # 1702-1), dilution 1:200,000. E-Cadherin Antibody,Rabbit Monoclonal B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-E-cadherin RabMAb (cat. # 1702-1). C. Immunohistochemical analysis of paraffin-embedded human hepatocellular carcinoma using anti-E-cadherin RabMAb (cat. # 1702-1). |