供应Amresco Albumin BovineⅤ 牛血清白蛋白Ⅴ 价格

Preparation Note

Serum albumin may be referred to as Cohn Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Cohn Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures ａnd distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock ａnd chromatography. Additional purification steps may include crystallization or charcoal filtration.

采用热休克分级分离法制备。

Biochem/physiol Actions

Certain conformational ａnd primary-sequence epitopes of BSA are suspected allergens in human beef ａnd milk allergies.¹

1. Restani, P., et al., Characterization of bovine serum albumin epitopes ａnd their role in allergic reactions Allergy 59 Suppl 78, 21-24, （2004）

Cohn, E.J., et al. J. Am. Chem. Soc. 68, 459, （1946）

Merck 14,8468