Alternate Names / Synonyms: human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP
Gene Symbol: BMP 2
Accession #: P12643
Gene ID: 650
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized without additives
Molecular Weight: 26.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the dose-dependent cytolysis of MC3T3-E1 cells is < 50 ng/ml.
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 ug BSA per 1 ug of protein). This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. BMP-2 is expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary, and small intestine. Recombinant human BMP-2 is a 26 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.