HIV-1 Integrase p31/重组艾滋病毒整合酶p31_详细资料

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HIV-1 Integrase p31/重组艾滋病毒整合酶p31

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HIV-1 Integrase p31/重组艾滋病毒整合酶p31
产品编号：HIV-145
产品规格：100μg/500μg/1mg

Introduction Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell ａnd is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization, a central catalytic domain ａnd a C-terminal domain. Both Central catalytic domain ａnd C-terminal domains have been shown to bind both viral ａnd cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally, several host cellular proteins interact with integrase ａnd may facilitate the integration process.

Description The E.coli derived recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the p31 protein （intergrase） 9-289 amino acids, fused with a GST tag at N-terminus.

Source Escherichia Coli.

Physical Appearance Sterile filtered colorless clear solution.

Formulation 1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X & 50% Glycerol.

Purity Greater than 95.0% as determined by HPLC analysis ａnd SDS-PAGE.

Stability HIV-1 Integrase p31 protein is shipped at ambient temperature.
Upon arrival, Store at -20°C.
Stable for Five years frozen. One month in solution at room temperature.

Specificity Immunoreactive with all sera of HIV-1 infected individuals.

Applications HIV-1 Integrase p31 antigen is suitable for ELISA ａnd Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.

Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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HIV-1 Integrase p31/重组艾滋病毒整合酶p31

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Introduction	Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell ａnd is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization, a central catalytic domain ａnd a C-terminal domain. Both Central catalytic domain ａnd C-terminal domains have been shown to bind both viral ａnd cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally, several host cellular proteins interact with integrase ａnd may facilitate the integration process.
Description	The E.coli derived recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the p31 protein （intergrase） 9-289 amino acids, fused with a GST tag at N-terminus.
Source	Escherichia Coli.
Physical Appearance	Sterile filtered colorless clear solution.
Formulation	1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X & 50% Glycerol.
Purity	Greater than 95.0% as determined by HPLC analysis ａnd SDS-PAGE.
Stability	HIV-1 Integrase p31 protein is shipped at ambient temperature. Upon arrival, Store at -20°C. Stable for Five years frozen. One month in solution at room temperature.
Specificity	Immunoreactive with all sera of HIV-1 infected individuals.
Applications	HIV-1 Integrase p31 antigen is suitable for ELISA ａnd Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
Usage	ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.