Introduction | SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies. |
Description | The E.coli derived 43 kDa recombinant protein contains the N-terminus Enevelope protein 1-76 amino acids immunodominant regions. |
Purification Method | SARS Envelope protein was purified by proprietary chromatographic technique. |
Purity | SARS Envelope protein is >95% pure as determined by 10% PAGE(coomassie staining). |
Formulation | 50mM Tris-HCl, 60mM NaCl, and 50% glycerol. |
Storage | SARS Envelope Protein is shipped at ambient temperature. Upon arrival, store at -200C. |
Stability | Five year frozen, 6 month at +40C. |
Specificity | SARS Envelope protein is Immunoreactive with sera of SARS-infected individuals. |
Applications | SARS Envelope antigen is suitable for ELISA and Western blots, excellent antigen for detection of SARS with minimal specificity problems. |
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |