25414 F（ab） Fragment of Goat anti-Mouse I...

F(ab) Fragment of Goat anti-Mouse IgG

F(ab) Fragment of Goat anti-Mouse IgG

Cross reactivity can be a problem when working with primary antibodies sourced from animal species that are evolutionary closely related to the source of tissues or cells that antigens are to be detected in.

An example is using a mouse monoclonal on rat tissue. With many monoclonal antibodies of mouse origin and some of rat, and the prevailing animal cells and tissues being used in studies likewise originating from rat or mouse, it often happens that cross reactivity occurs, leading to false positive results.

A second problem that derives from cross-reactivity occurs in double labeling, when using primary antibodies from closely related animal sources. With this in mind, Aurion has developed two series of new conjugates: