PML/RARA融合基因检测试剂盒荧光原位杂交法
广州健仑生物科技有限公司
我司还有很多荧光原位杂交系列检测试剂盒以及各种FISH基因探针和染色体探针等,。
急性早幼粒细胞白血病(APL)是急性髓细胞白血病(AML)的一种特殊类型(M3),占所有AML病例的10%-15%。APL具有独特的临床表型及细胞形态学、细胞遗传学和分子生物学特征。目前发现约95%的APL患者伴有异常染色体核型t(15;17)(q22;q21),该易位使15号染色体上的PML基因与17号染色体上的RARA基因发生相互易位形成PML/RARA融合基因,是APL的一个特异分子标志。PML/RARA融合蛋白通过显性负YZ作用YZ早幼粒细胞分化成熟,从而阻断细胞分化导致持续增殖。
PML/RARA融合基因检测试剂盒荧光原位杂交法
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以下是我司出售的部分FISH产品:
p53/RB1/ATM/CSP12/D13S25基因探针 |
5q33/5q31/D7S486/D7S522/CSP8/D20S108/XY基因探针 |
4/10/17/KMT2A[ETV6RUNX1]/[BCRABL(DF)]基因探针 |
p53/D13S319/RB1/1q21/IGH基因探针 |
13/16/18/21/22/XY染色体计数探针 |
ALK(2p23)基因断裂探针 |
EML4/ALK融合基因 t(2;2); inv(2) 探针 |
1p和19q探针 |
KIT(4q12)基因探针(红色) |
SS18(18q11)(SYT)基因断裂探针 |
C-MET(7q31)基因探针 |
ROS1(6q22)基因断裂探针 |
ERCC1(19q13)基因探针 |
hWAPL(10q23)基因探针 |
AR基因扩增检测探针 |
MDM4(1q32)基因探针 |
12号染色体计数探针(绿色) |
CBFB/MYH11融合基因inv (16), t (16;16)探针 |
TCF3/ PBX1融合基因t (1;19)探针 |
ESR1(6q25)基因探针 |
FGFR1(8p11)基因探针 |
p53/RB1/ATM/CSP12/D13S25基因探针(独立 ) |
p53/D13S319/RB1/1q21/IGH基因探针(独立) |
NUP98基因断裂检测探针 |
NTRK1(1q22-q23.1)基因断裂探针 |
RET(10q11)基因断裂探针 |
PIK3CA(3q26)基因探针 |
TFE3(Xp11.2)基因断裂探针 |
FGFR1(8p11)基因断裂探针 |
3号染色体计数探针(绿色) |
7号染色体计数探针(绿色) |
17号染色体计数探针(绿色) |
10号染色体计数探针(绿色) |
X染色体检测探针 |
Y染色体计数探针(红色) |
13号染色体检测探针 |
MLAA-34(13q14)基因探针 |
全世界数以百万计的人依靠常规透析来完成病变或受损肾脏的作用,而干细胞疗法被认为是Z有希望替代透析技术挽救患者的一种途径。
昨日,一项具有突破性进展的成果刊登在注明学术期刊《干细胞报告》上,英国研究人员*次成功在活生物体内利用干细胞技术培育出了可以正常过滤宿主血液并产生尿液的人类肾组织,这可能成为shenbingZL史上一个重要成就。
由曼彻斯特大学两位教授领衔的研究团队先在实验室培养皿营养液环境中把人类胚胎干细胞培养成肾小球,然后将培养出来的肾小球与类似结缔组织的凝胶物混合后注入到实验小鼠下。
能够过滤血液以产生尿液的功能性人“小型肾脏”已经在YL领域中的活生物体中生长,这标志着朝向ZLshenbing的重要步骤。
研究人员已经能够将人类干细胞发展成为“比先前报道的发现显着更成熟”的小型肾脏。
它具有功能完好的人体血管并能够过滤其宿主的血液。
来自曼彻斯特大学的研究小组能够通过在小鼠中进行肾脏生长的Z后阶段而不是培养皿来产生他们的进步。
该项目的负责人,该大学生物,医学和健康学院的Susan Kimber教授告诉独立报,“以前没人做过这件事” 。
“我们是*个把这些肾细胞投入到体内 [生活]环境中,并显示它们可以发挥功能”。
研究小组表明,注射到小鼠体内的荧光染料正从血液中过滤并进入肾小管。
“肾小管的工作是选择性地重吸收关键分子,主要是盐分,还有葡萄糖等,以防止它们被浪费,我们也看到了这一点
The Georgian capital city of Tbilisi. A 5 year old boy looked out from the window of the living room with a black flag on the neiourhood's balcony. A day earlier, the Tbilisi anti Soviet strike parade to increase the number of thousands of people, the Soviet army sent tanks to disperse protesters, killing 19 people, hundreds of people were injured. The black flag, in any time and country, stands for mourning and silent resistance.
The boy's name is Zaza pachulia.
If life was a movie, this shot set the tone for what happened later. The next 20 years, will often think of the moment of patchogue faria. Maybe the sunshine is just right that day, and the white clouds are floating in the blue sky. But the black flag is like a nightmare, which is always entangled with his life. The distance of the picture may also be crowed by the crowd's pain and the long dispersed smoke.
Regardless of Ariza is not dirty X twists and turns of his life to l you that aggression is genetically determined......
Regardless of Ariza is not dirty X twists and turns of his life to l you that aggression is genetically determined......
Compared to many ordinary families, patchogue Faria childhood lucky. David - patchogue Faria, his father is the former Soviet Judo champion; Marina patchogue Faria, his mother is the former Soviet Union's women's basketball team. He was able to read one of the only two private schools in Georgia, even if he had to pay a high tuition fee of $500 a year. But when Georgia finally gained independence in 1991, and the whole country was forced to rebuild a large number of infrastructure, and tap water and electricity became luxury items, the richness of a small family could not be matched by the collapse of the whole country.
Patchogue Faria has inherited the excellent genes, he soon than all the children of the same age are high, he through sporadic evision and video that the ocean has a called NBA Basketball League, and very yearning. In Georgia a thousand things wait to be done there is no place to display their home, patchogue Faria his athleticism.
In early 1998, finally turning point, patchogue Faria called into the principal's office, told the Turkey national team coach took a fancy to him. Completed a preliminary trial in patchogue Faria school basketball hall, a Turkey Basketball League club soon decided to raise him, for the school education, housing, meals and all other conditions for him.
That year seems to be the only option for Georgian sports practitioners. Many Olympic champions fled in the 10 years after the declaration of independence in Georgia, and they spread to Russia, Europe, and of course Turkey and other countries.
But the club in Istanbul, 800 miles from Tbilisi, patchogue Faria was just a child. Dawit think twice, decided to quit the job, and patchogue Faria to go to Turkey. "We have a very close relationship," patchogue Faria often recall father, "Turkey is the big city life, only us, two Georgians have each other each other."
According to the movie plot, it will be an inspirational story similar to "wrestling dad". David very maintain his son, he will attend the patchogue Faria every game, a conflict in patchogue Faria, he excitedly rushed into the floor.
"He taught me a lot of things, family, honor and respect," said "he taught me patchogue Faria, how to be a man." But life is always harder than a movie. On June 30, 1998, Tbilisi returned to patchogue Faria had his first summer vacation, he suffered a heart attack davitt died unexpectedly, he had 7 months to 40 years of age.
Regardless of Ariza is not dirty X twists and turns of his life to l you that aggression is genetically determined......
That afternoon, patchogue Faria returned home, found his father was not at home, only to neiors for a few hours, my mother from work. When Marina came back, it was immediay found that something was wrong. Dawit ended his judo career for 15 years. He gained weight and smoked a whole pack of cigarettes a day. Before that, he had gone through two heart attacks. He had been receiving regular medication and regular hospital reviews.
In the death of Dawit to go to the hospital to check on the steps, Marina learned this news spreads out, young also cried patchogue faria. He should have returned to Istanbul for a few weeks to report to the club, but he thought at the time, "I should give up my dream and help my mom through these difficult times."