Nexus 128 3D Systems | Slice-Based 2D Systems | Impact |
True 3D imaging | • | • | 3D detector and 3D reconstruction algorithm yield full volumetric images of target tissue with every laser pulse. |
4D scanning (volume + time) | • | • | 4D scans enable analysis of multiple volumes of interest simultaneously without compromised image quality. |
3 second dynamic mode | • | • | Full volumetric (3D) dynamic scanning speeds as low as 3 seconds without compromised image quality. |
Isotropic image volumes | • | • | 3D reconstruction with resolution equal in all directions is unaffected by animal positioning. |
Ability to image broad range of fluorescent molecular probes | • | Not Always | Ability to image tail vein injected NIR molecular probes, e.g., Alexa Fluor® 680 & 700 and CyTM5.5. |
Multispectral imaging | • | • | Mutliple wavelength scans (680-950nm) enable tissue differentiation based on optical absorption. |
Molecular probe uptake and distribution | • | • | Ability to locate and quantify targeted molecular probes. |
Image endogenous and/or exogenous probes | • | • | Generate images of vasculature without contrast agent or vasculature and probe when NIR probe is injected. |