3-arm-PS 4-arm-PS 8-arm-PS 8-arm-...

3-arm-PS  4-arm-PS 8-arm-PS  8-arm-P2VP

3-arm-PS  4-arm-PS 8-arm-PS  8-arm-P2VP

3-arm-PS  4-arm-PS 8-arm-PS  8-arm-P2VP

3-arm-PS  4-arm-PS 8-arm-PS  8-arm-P2VP

常用的胶束载体材料：

合成高分子材料：

亲水部分：PEG、PEO、PVP、PVA

疏水部分：PLGA、PLA、PCL、His、Poly(L-lysine)、Poly(L-Glutamic acid)、Poly(L-aspartic acid)、PEI、PS

天然高分子材料：

亲水部分：壳聚糖、海藻酸盐、葡聚糖、肝素、葡萄糖

疏水部分：DSPE、PE、胆固醇、BSA

嵌段共聚物胶束应用：

(1)抗肿瘤药物胶束

(2)抗真菌药物胶束

(3)KY药物胶束

(4)透过血脑屏障

(5) 基因传递

(6) 药物包封和药物传递

PS-b-PEO

Poly(styrene)-b-poly(ethylene oxide)

聚苯乙烯-聚氧乙烯

PEO 分子量：350/550/750/1000/2000/3000/5000/10000/20000

PS分子量：as required

PMMA-b-PEO

聚甲基丙烯酸甲酯-b-聚氧乙烯

Poly(methylmethacrylate)-block-poly(ethylene oxide) (PMMA-b-PEO)

PEO 分子量：350/550/750/1000/2000/3000/5000/10000/20000

PMMA分子量：as required

PS-b-PMMA

聚苯乙烯-b-聚甲基丙烯酸甲酯

Poly(styrene)-block-Poly(methyl methacrylate)

PMMA分子量：as required

PS分子量：as required 

PS-b-P4VP

Poly(styrene)-block-poly(4-vinylpyridine)

聚苯乙烯-聚(4-乙烯基吡啶)

P4VP分子量：as required

PS分子量：as required 

Poly(styrene), 10-arm star polymer / Core: diethylene glycol dimethacrylate

10-arm-PS

Poly(styrene), 3-arm star polymer / Core: mesitylene

3-arm-PS

Poly(styrene), 4-arm star polymer / Core: 1,2-bis(methylsilyl)ethane

4-arm-PS

Poly(styrene), 3-arm star polymer / Core: 2,4,6-tripropoxy-1,3,5-triazine

Poly(styrene), 8-arm star polymer / Core: tetrakis(2-silylethyl)silane

8-arm-PS

Poly(styrene), star polymers / Core: oligo([1,2-co-1,4]-butadiene)

Poly(2-vinyl pyridine), 8-arm star polymer / Core: tetrakis(2-silylethyl)silane

8-arm-P2VP

Poly(butadiene)-b-poly(styrene), 4-arm block star / Core: 1,2-bis(methylsilyl)ethane

4-arm PBd-PS

Poly(tert-butyl acrylate)-b-poly(styrene), multi-arm block star / Core: ethylene glycol dimethacrylate

Poly(ε-caprolactone)-b-poly(ethylene oxide), 4-arm block star / Core: pentaerythritol

4-arm PCL-PEO

Poly(ethylene oxide)-b-poly(adipic anhydride), 4-arm block star / Core: pentaerythritol

Poly(ethylene oxide)-b-poly(ε-caprolactone), 4-arm block star / Core: pentaerythritol

4-arm-PEO-PCL

Poly(ethylene oxide)-b-poly(lactide), 4-arm block star / Core: pentaerythritol

4-arm-PEO-PLA

Poly(ethylene oxide)-b-poly(2-methyl oxazoline), 4-arm block star / Core: pentaerythritol

Poly(ethylene oxide)-b-poly(propylene oxide), 4-arm block star / Core: pentaerythritol

Poly(2-hydroxyethyl methacrylate)-b-poly(methyl methacrylate–co–n-butyl methacrylate), 36-arm block star / Core: diethylene glycol dimethacrylate

Poly(lactide)-b-poly(ethylene oxide), 4-arm block star / Core: pentaerythritol

4-arm-PLA-PEO

Poly(methyl methacrylate)-b-poly(styrene), 8-arm block star / Core: α-Cyclodextrin

8-arm-PMMA-PS

Poly(styrene)-b-poly(methyl methacrylate), 14-arm block star / Core: α-Cyclodextrin

Graft Copolymers

Poly(acrylic acid)-graft-poly(ethylene oxide)

PAA-g-PEO   聚丙烯酸-接枝-聚氧乙烯

Poly(acrylic acid)-graft-poly(ethylene oxide), grafting on amide/imide linkage

Poly(methyl methacrylate)-graft-poly(ethylene oxide)

PMMA-g-PEO  聚甲基丙烯酸甲酯-接枝-聚氧乙烯

Poly(methyl methacrylate–co–[isobutryl ethylmethacrylate–graft–polystyrene])

Poly(ε-caprolactone)-graft-poly(ethylene oxide)

PCL-g-PEO   聚已内酯-接枝-聚氧乙烯

Poly(styrene)-graft-poly(acrylic acid), grafting on backbone

PS-g-PAA  聚苯乙烯-接枝-聚丙烯酸

西安瑞禧生物科技有限公司

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