TUBB3 Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
别名
TUBB3, CDCBM, Beta III Tubulin, Class III beta-tubulin, TUBB4, Tubulin, beta 3, Tubulin beta-III, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin, beta 3 class III, CFEOM3A
克隆类别
Polyclonal
反应种属
Human, Mouse, Rat
来源宿主
Rabbit
应用
WB 1:1000-1:5000 IHC 1:50-1:200
特异性
Tubulin beta Antibody detects endogenous levels of total Tubulin beta
性能
保存方法
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
浓度
1mg/ml
分子量
55kDa
功能
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
纯化方法
Immunogen affinity purified
亚细胞定位
Cytoplasm,Cytoskeleton,
组织专一性
Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues.