成纤维细胞生长因子,fgf-8b,雄激素诱发的生长因子,肝素结合生长因子
Description :
peprotech Human FGF-8描述:
FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8 (FGF-8b) is a 22.4 kDa protein consisting of 193 amino acid residues.
peprotech Human FGF-8是一种肝素结合生长因子属于FGF家族。此家庭的蛋白质在产前发育和出生后的生长和再生的各种组织中发挥核心作用,促进细胞增殖和分化。有4个已知的交替剪接形式的FGF8;FGF8a,fgf-8b,fgf-8e和fgf-8f。人类和小鼠FGF8 A和B是相同的人类和小鼠FGF8 E和F 98%是完全相同的。FGF-8目标乳腺癌细胞和其他细胞的成纤维细胞生长因子受体的表达。重组人FGF-8(fgf-8b)是一个22.4 kDa的蛋白由193个氨基酸残基组成。
Catalog #:
目录#:
100-25
100-25
Source :
来源:
E.coli
大肠杆菌
Purity :
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
大于95%的SDS-PAGE凝胶电泳和GX液相色谱分析。
Endotoxin Level :
内毒素水平:
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
内毒素水平低于0.1毫微克每µG(1eu /µG)。
Biological Activity :
生物活性:
The ED 50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
ED 50由胸苷吸收的剂量依赖性的刺激表达FGF -确定≤BaF3细胞受体是0.5毫微克/毫升,对应于一个特定的≥2×106单位/毫克的活性。
Selected References :
选定引用:
Selected List of References Citing This Product
引用该产品的引用列表
AA Sequence :
氨基酸序列:
MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR
mqvtvqsspn ftqhvreqsl vtdqlsrrli rtyqlysrts gkhvqvlank rinamaedgd pfaklivetd tfgsrvrvrg aetglyicmn kkgkliaksn gkgkdcvfte ivlennytal qnakyegwym aftrkgrprk gsktrqhqre vhfmkrlprg hhtteqslrf eflnyppftr slrgsqrtwa PEPR
PubMed Link :
PubMed链接:
FGF-8
FGF-8
Country of Origin :
原产国:
USA
美国
Special Sizes:
特殊尺寸:
Many products can be ordered in custom sizes. Please click here to contact with your request.
许多产品可以订购定制的尺寸。请点击这里您的要求。
Usage:
使用:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
仅用于研究。不用于诊断或ZL程序。
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