The Thermo Scientific Acclaim HILIC-10 column is designed for separating highly hydrophilic molecules by hydrophilic interaction liquid chromatography (HILIC). This column is suited for use in a broad range of applications, including separation of hydrophilic drugs and drug metabolites.
- Retains highly polar molecules that are not retained by reversed-phase chromatography
- Unique selectivity, complementary to reversed-phase columns
- Hydrolytically stable
- Rugged column packing
- Broad application range
The advantage of the Acclaim HILIC-10 phase is the compatibility with up to 20% aqueous phase, while maintaining affinity for polar analytes. Acclaim HILIC-10 columns are available in 3 μm particle size. A variety of column formats are available: 4.6 × 150 mm, for high-throughput routine analysis; 3.0 × 150 mm, for high-throughput analysis with reduced solvent consumption; and 2.1 × 150 mm, for LC-MS analysis.