线粒体内膜转位同源蛋白9抗体
英文名称 TIMM9
中文名称 线粒体内膜转位同源蛋白9抗体
别 名 Mitochondrial import inner membrane translocase subunit Tim9; TIM9; TIM9_HUMAN; TIM9A; Timm9; TIMM9A.
说 明 书 0.2ml
研究领域 细胞生物 染色质和核信号 信号转导
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TIMM9
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]
Function:
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Subunit:
Heterohexamer; composed of 3 copies of TIMM9 and 3 copies of TIMM10/TIM10A, named soluble 70 kDa complex. The complex forms a 6-bladed alpha-propeller structure and associates with the TIMM22 component of the TIM22 complex. Interacts with multi-pass transmembrane proteins in transit. Also forms a complex composed of TIMM9, TIMM10/TIM10A and FXC1/TIM10B.
Subcellular Location:
Mitochondrion inner membrane.
Tissue Specificity:
Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.xy-0294R-FITxy Rabbit Anti-Goat IgG/FITCFITC标记的兔抗羊IgG
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xy-0358R-xyy5 Rabbit Anti-Guinea pig IgG/Cy5Cy5标记的兔抗豚鼠IgG
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xy-0358R-AF350 Rabbit Anti-Guinea pig IgG/Alexa Fluor 350Alexa Fluor 350标记的兔抗豚鼠IgG
xy-0358R-AF488 Rabbit Anti-Guinea pig IgG/Alexa Fluor 488Alexa Fluor 488标记的兔抗豚鼠IgG
xy-0358R-Axy Rabbit Anti-Guinea pig IgG/AP碱性磷酸酶(AP)标记的兔抗豚鼠IgG
xy-0358R-FITxy Rabbit Anti-Guinea pig IgG/FITCFITC标记的兔抗豚鼠IgG
xy-0358R-AF555 Rabbit Anti-Guinea pig IgG/Alexa Fluor 55lexa Fluor 555标记的兔抗豚鼠IgG
xy-0358R-AF647 Rabbit Anti-Guinea pig IgG/Alexa Fluor 647Alexa Fluor 647标记的兔抗豚鼠IgG