色氨酸2,3双加氧酶抗体

色氨酸2,3双加氧酶抗体

英文名称 TDO2/tryptophan 2,3-dioxygenase
中文名称 色氨酸2,3双加氧酶抗体
别    名 tryptophan 2,3-dioxygenase; 3-dioxygenase; T23O_HUMAN; TDO 2; TDO; tdo2; TO; TPH2; TRPO; Tryptamin 2 3 dioxygenase; Tryptamin 2; Tryptophan 2 3 dioxygenase; Tryptophan 2; Tryptophan oxygenase; Tryptophan pyrrolase; Tryptophanase.
  
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TDO2/tryptophan 2,3-dioxygenase
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]

Function:
Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin 

Subunit:
Homotetramer (By similarity).

Similarity:
Belongs to the tryptophan 2,3-dioxygenase family.xy-0374R    Rabbit Anti-horse IgM兔抗马IgM
xy-0297G    Goat Anti-human IgG羊抗人IgG
xy-0297R    Rabbit Anti-human IgG兔抗人IgG
xy-0360R    Rabbit Anti-human IgA兔抗人免疫球蛋白A
xy-0377R    Rabbit Anti-mouse IgG-Fc兔抗小鼠IgG-Fc
xy-0309R    Rabbit Anti-pig IgG兔抗猪IgG
xy-0309Rs    Rabbit anti-Pig IgG whole serum兔抗猪IgG抗血清
xy-0293Rs    Rabbit anti-Rat IgG whole serum兔抗大鼠IgG抗血清
xy-0293M    Mouse Anti-rat IgG小鼠抗大鼠IgG
xy-0293R    Rabbit Anti-rat IgG兔抗大鼠IgG
xy-0295M    Mouse Anti-rabbit IgG小鼠抗兔IgG
xy-0296R    Rabbit Anti-mouse IgG兔抗小鼠IgG
xy-0335R    Rabbit Anti-Monkey IgG兔抗猴IgG
xy-0346R    Rabbit Anti-rat IgM兔抗大鼠IgM
xy-0369M    Mouse Anti-Rabbit IgM小鼠抗兔IgM
xy-0346Rs    Rabbit anti-Rat IgM whole serum兔抗大鼠IgM抗血清
xy-0295Gs    Goat anti-Rabbit IgG whole serum羊抗兔IgG抗血清
xy-0295xys    Donkey anti-Rabbit IgG whole serum驴抗兔IgG抗血清
xy-0368G    Goat Anti-Mouse IgM羊抗小鼠IgM
xy-0293G    Goat Anti-rat IgG羊抗大鼠IgG
xy-0358G    Goat Anti-Guinea pig IgG羊抗豚鼠IgG
xy-0345G    Goat Anti-human IgM羊抗人IgM
xy-0294M    Mouse Anti-Goat IgG小鼠抗羊IgG
xy-0312R    Rabbit Anti-Avidin兔抗亲和素
xy-0311R    Rabbit Anti-Biotin兔抗生物素抗体IgG
xy-0327R    Rabbit Anti-Bovine IgM兔抗牛IgM
xy-0314R    Rabbit Anti-chicken IgM兔抗鸡IgM
xy-0303R    Rabbit Anti-dog IgG兔抗狗IgG
xy-0370R    Rabbit Anti-Goat IgM兔抗羊IgM
xy-0358R    Rabbit Anti-Guinea pig IgG兔抗豚鼠IgG
xy-0375R    Rabbit Anti-Guinea pig IgM兔抗豚鼠IgM