Xanthohumol

Xanthohumol
Product Name: Xanthohumol
Alternate Name/Synonyms: (2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)- 2-propen-1-one
Description: Cell-permeable. A bioactive flavonoid antioxidant found in the flowering hops plant. Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II). Impairs prostate cancer cell growth and proliferation.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 6754-58-1
Molecular Formula: C21H22O5
Molecular Weight: 354.4
Purity: ≥98% by TLC
Solubility: DMSO (~35 mg/ml) or EtOH (~35 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack Protect from light and moisture
Handling:
USAGE: For Research Use Only! Not For Use in Humans