Metal-Regulatory Transcription Fact...

Metal-Regulatory Transcription Factor 1 (MTF1) (C-Term) 抗体

抗原
Metal-Regulatory Transcription Factor 1 (MTF1)
别名 MTF-1, MTF1, mtf1, MGC86485, Thyls, ZRF
抗原表位
其他选择 C-Term
AA 41-140(5),AA 41-141 (2),C-Term (2)
适用
其他选择 Murine, Rat ((Rattus)), Dog (Canine), Bovine, Human
Human(22),Bovine (13),Dog (Canine) (13),Murine (13),Rat ((Rattus)) (13),Pig (Porcine) (12)
宿主
其他选择 Rabbit
Rabbit(14),Mouse (8)
克隆类型
多克隆
标记
其他选择 非结合性
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
应用范围
其他选择 Western Blotting (WB)
Immunofluorescence (Paraffin-embedded Sections) (IF (p))(10),ELISA (8),Western Blotting (WB) (8),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3)
[Pubmed] 1 reference available
规格 100 μg
发货至 ZG (更改)
发货时间 9至12个工作日

Metal-Regulatory Transcription Factor 1 (MTF1) (C-Term) 抗体

产品细节

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免疫原 Synthetic peptide directed towards the C terminal of human MTF1
序列 QSSLVMGEQN LQWILNGATS SPQNQEQI ASKVEKVFFT TAVPVASSPG
预测反应 Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Guinea pig : 90 %, Rabbit : 90 %
产品特性 This is a rabbit polyclonal antibody against MTF1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified

目标详细情况

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Metal-Regulatory Transcription Factor 1 (MTF1) (C-Term) 抗体目标详细情况

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别名 MTF1
背景 The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.
分子量 81 kDa
基因ID 4520
NCBI Accession NM_005955, NP_005946
UniProt Q14872
研究领域 Chromatin and Nuclear Signaling, Transcription Factors

使用细节

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Metal-Regulatory Transcription Factor 1 (MTF1) (C-Term) 抗体使用细节

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应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 753 AA

限制 For Research Use only

贮存及处理

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贮存及处理

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状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C

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