重组丙型肝炎病毒NS3基因型-1b产物/HCV NS3 Genotype-1b_详细资料

产品信息 重组丙型肝炎病毒NS3基因型-1b产物/HCV NS3 Genotype-1b 产品编号：HCV-204 产品规格：100μg/500μg/1mg Catalogue Number HCV-204 Introduction HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). Description The E.coli derived 26.2 kDa recombinant protein contains the HCV NS3 c33c immunodominant regions. The 252 amino acid protein is fused to 6xHis tag. Purification Method Purified by proprietary chromatographic technique. Purity HCV NS3 Genotype-1b protein is >95% pure as determined by 10% PAGE (coomassie staining). Formulation 50mM NaPO4 pH 8.3 and 10mM DTT. Storage HCV NS3 Genotype-1b although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. Sequence Starts: MRDSDSQTFQ Ends: DSVIDCNTCVT. Specificity Immunoreactive with sera of HCV-infected individuals. Applications HCV NS3 Genotype-1b antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems. Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Catalogue Number	HCV-204
Introduction	HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Description	The E.coli derived 26.2 kDa recombinant protein contains the HCV NS3 c33c immunodominant regions. The 252 amino acid protein is fused to 6xHis tag.
Purification Method	Purified by proprietary chromatographic technique.
Purity	HCV NS3 Genotype-1b protein is >95% pure as determined by 10% PAGE (coomassie staining).
Formulation	50mM NaPO4 pH 8.3 and 10mM DTT.
Storage	HCV NS3 Genotype-1b although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Sequence	Starts: MRDSDSQTFQ Ends: DSVIDCNTCVT.
Specificity	Immunoreactive with sera of HCV-infected individuals.
Applications	HCV NS3 Genotype-1b antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.