Human Myostatin/重组人肌肉生长YZ素

Human Myostatin/重组人肌肉生长YZ素
产品编号：100-255
产品规格：10μg
Description: Myostatin is a TGF-beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin. Recombinant Human myostatin is a 25.0 kDa protein consisting of two identical 109 amino acid polypeptides linked by a single disulfide bond.
Source: E. coli
Molecular Weight: 25 kDa
Purity: > 98% by SDS-PAGE and HPLC analysis
Endotoxin level/内毒素水平: < 0.1 ng per μg of Myostatin
Stabilizer: none
Formulation: lyophilized
Biological Activity: Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected for this effect is 17.0-25.0 ng/ml.
Reconstitution: The human Myostatin should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. Note: It is recommended that further dilutions should be made in a low pH buffer containing BSA and stored at -20°C for future use.
Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted human Myostatin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles.
Usage: Human Myostatin offered for research use. Not for drug use. Not for human use.