Human GLP-1/重组人胰高血糖素样肽-1

Human GLP-1/重组人胰高血糖素样肽-1
产品编号：100-339
产品规格：1000μg
Description: GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
Source: E. coli
Molecular Weight: 3.3 kDa
Purity: 98 % (SDS-PAGE, HPLC)
Endotoxin level/内毒素水平: < 0.1 ng per ug of GLP-1
Stabilizer: none
Formulation: lyophilized
Biological Activity: Data not available!
Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C.
Avoid repeated freeze-thaw cycles.
Usage: Human GLP-1 is offered for research use. Not for drug use. Not for human use.