Anti-GLIS2抗体,GLIS2蛋白抗体 产品说明【产品介绍】:
GLIS2 is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family. By recruiting the corepressors CtBP1 and HDAC3, GLIS2 represses the transcriptional activation mediated by ∫-catenin in the Wnt pathway. GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation. Mutations of GLIS2 may be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis. GLIS2 contains five tandem Cys(2)-His(2) zinc finger motifs that exhibit the highest homology to those of members of the GLI and Zic subfamilies of Krüppel-like proteins. GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta.
此产品本公司有标记的一抗出售,相关标记有:FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记、Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记
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产品信息:
【产品编号】:HRK-11566R
【英文名称】:Anti-GLIS2 antibody
【中文名称】:GLIS2蛋白抗体
【产品别名】:NPHP7; NKL; GLI kruppel family member 2; GLI similar 2; GLI-similar 2; GLIS 2; GLIS family zinc finger 2; glis2; GLIS2_HUMAN; Kruppel like zinc finger protein GLIS2; Neuronal Krueppel-like protein; Tax helper protein; THP; Zinc finger protein GLI2; Zinc finger protein GLIS2.
【抗体来源】:Rabbit or Mouse
【克隆类型】:Polyclonal or monoclonal
【产品应用】(仅供参考具体情况需来电详细咨询确认):WB、ELISA、IP、IHC-P、IHC-F、IF等
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
【性 状】:Lyophilized or Liquid111
【浓 度】:1mg/1ml
【亚 型】:IgG
【纯化方法】:affinity purified by Protein A
【保存条件】:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4°C.