25 tests Anti-Human CD161 Alexa Fluor® ...

Description: This HP-3G10 monoclonal antibody reacts with CD161 （also known as NKR-P1A）, a member of the C-type lectin superfamily. The human homologue of NK1.1 in C57BL/6 mice, CD161 is expressed on natural killer cells and is upregulated in response to IL-12. CD161 can also be detected on various T cell subsets, including memory/effector CD4+ T cells, CD8+ T cells, gamma delta TCR T cells, and a subset of CD3+ thymocytes. Finally, CD161 expression has been demonstrated on human Th17 CD4+ T cells. The function of this receptor is unclear although studies suggest a possible stimulatory role. Nevertheless, Lectin-like transcript-1 （LLT1）, which is also known as osteoclast inhibitory lectin, has been identified as the ligand for CD161.