anti-MMP-26(Matrix metalloproteinase-26)抗体 瑞齐生物抗体应用于WB、IHC、IF、ELISA等实验中“
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【产品名称】:
anti-MMP-26(Matrix metalloproteinase-26)抗体
【产品规格】:0.1ml/0.2ml
【产品价格】:询价(电询或客服)
【抗体来源】:Rabbit OR Mouse or Goat
【产品用途】:科研实验,用于ELISA实验、免疫组化实验,WB实验,IF实验等,可,索取产品说明书!
【性 状】: Lyophilized or Liquid
【浓 度】: 1mg/1ml
【亚 型】: IgG
【贮 存】: 贮存于-20℃.
【相关标记】:HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【产品别名】:
anti-MMP-26(Matrix metalloproteinase-26)抗体 ,多肽抗原,蛋白抗体Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.
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