产品英文名称:TGF-β1,human
产品中文名称:人TGF-β1蛋白
订购:
:gnana@hystemcell.com
TGF-β1产品介绍:
TGF-β1是一组蛋白超家族。TGF-β1是由两个结构相同或相似,分子量为12.5kD的亚单位通过二硫键连接而成的双体。在人的心肌成纤维细胞、血 管内皮细胞和巨噬细胞等均有表达。TGF-β1信号通路的关键传导分子为胞质蛋白Smads,他们可以将TGF-β1信号直接由细胞膜受体传导人细胞核 内,是受体激酶介导的细胞内信号传导的新途径,为细胞信号跨膜后与核内基因转录之间开通了一条简便路径。不同的Smad介导不同的TGF-β1家族成员的 信号转导。TGF-β1/Smad信号转导通路活化后,可以促进相关基因的转录,如胶原蛋白的表达ZG,也可通过调节MMPs/TIMPs表达的平衡YZ 胶原降解,促进组织纤维化。
TGF-β1产品特性:
» TGF-β1活性经过人源细胞鉴定,纯度高。
» 生物活性在人源293细胞经过SMAD实验鉴定The EC50为 0.1–1.0 ng/ml。
» TGF-β1产品经过SDS-PAGE 和HPLC双层鉴定纯度大于95%。
TGF-β1产品英文简述:
Members of TGF-family are multifunctional cytokines that regulate cell proliferation, growth, differentiation and migration as well as synthesis of the extracellular matrix. The three human isoforms, TGF- 1, 2, 3, signal through the same receptor and elicit similar biological responses. The release of biologically active TGF-isoform from a latent complex involves proteolytic processing of the complex. TGF-1 is the most abundant isoform secreted by almost all cell types. Human TGF-1 is a 25.0kDa protein with each subunit containing 112 amino acid residues, linked by a disulfide bond.
? Purity: Greater than 95% as determined by SDS-PAGE and HPLC analyses
? Biological Activity: The activity was determined by using a SMAD reporter gene assay in human 293 cells. The EC50 ranges from 0.1 – 1.0 ng/ml.
? For Research Use Only. Not for Use in Humans.
一切干细胞实验耗材优惠尽在华雅思创生物
2015年统统促销价,价格Z低-一切活动尽在上海华雅思创!
以下是促销部分产品,更多请
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StemRD MGro-500 MSC medium,chemically-defined,间充质干细胞培养基 500mL/瓶
LONZA 04-418Q X-VIVO 15 无血清培养基 1L/瓶
Life Technology 087-0112DK AIM-V? CTS? 无血清细胞培养基(细胞ZL级) 1000mL/瓶
Pall 15950-017 Ultroser Serum Substitute 血清替代品 20mL/瓶
LONZA 12-725F UltraCULTURE Serum-free Medium无血清培养基 500mL/瓶
BD 762165 PAXgene Blood RNA Tube RNA样本收集管 100管/盒
LONZA 50150 SeaKem? Gold Agarose 金琼脂糖粉 125g/瓶
LONZA CC-3162 EGM-2 BulletKit( CC-3156 & CC-4176 )套装 Kit/套
Nunc 159910 175cm2易用培养瓶,PS,已灭菌,瓶盖:过滤盖 30个/箱
LONZA LT07-318 MycoAlert? Mycoplasma Detection Kit支原体检测试剂盒 100Tests/盒
LONZA LT07-418 MycoAlert? Mycoplasma Detection Kit支原体检测试剂盒 50Tests/盒
Lonza 50-650U Kinetic-QCL 192 Test Kit内毒素检测试剂盒 192T/盒
Corning 431080 175cm⒉细胞培养瓶,Angled颈,透气盖 50个/箱
Corning 8388 125mL储液瓶 Storage Bottles,PS,45mm瓶颈,带盖,灭菌,独立包装 24个/箱
Corning 430659 2ml冻存管, 聚丙烯,外旋盖, 可自立圆底 500个/箱
Corning 3290 75cm2 CellBIND Surface培养瓶,已灭菌,透气盖 100个/箱
Corning 3292 175cm2 CellBIND Surface培养瓶,已灭菌,透气盖 50个/箱
BD-Falcon 352360 Cell Strainer, 100μm, Yellow 100um细胞滤网 50个/箱
BD Falcon 352070 50mL锥形离心管,高透明度聚丙烯,袋装 500支/箱
BD Falcon 352096 15mL锥形离心管,高透明度聚丙烯,袋装 500支/箱
BD BioCoat 354234 Matrigel Basement Membrane Matrix(标准型) 10mL/瓶
Cygnus F550 CHO HCP ELISA Kit,3G宿主蛋白检测试剂盒 96T/盒
Cygnus F410 E.coli HCP ELISA Kit 大肠杆菌 96T/盒
Nalgene 5100-0001 Cryo 1℃ Freezing Container梯度降温冻存盒 1个/箱
Nalgene 5026-0909 CryoBoxes 冻存盒 9X9 阵列,管瓶1.2/2.0mL 24个/箱
Nalgene 2250-0130 50L 可高温高压操作的细口大瓶(带手柄) 1个/箱
Nalgene 2319-0050 20L 可高温高压灭菌的细口大瓶(带放水口) 1个/箱
Hyclone SH30084.03 FBS 优等澳洲胎牛血清 500mL/瓶
PeproTech 100-18B-500 Recombinant Human FGF-basic (154 a.a.)因子 500ug/支
Parafilm PM-996 Parafilm? M Laboratory Film 封口膜 12卷/箱