sigma 91077C CAS 11061-68-0 重组人胰岛素 Insulin Recombinant Human

重组人胰岛素 Insulin Recombinant Human
91077C - dry powder, for research or for further manufacturing use
别名: Insulin sodium salt human, rh-Insulin
CAS号: 11061-68-0
酶学委员会编号: 234-279-7
 
91077C-1G
91077C-5G
91077C-10G

重组人胰岛素 Insulin Recombinant Human 相关类型 Cell Culture, Hormones, Reagents and Supplements
Quality Level GMP
form dry powder
potency ≥27.5 units per mg
storage temp. −20°C

描述
Application
Serum-free medium supplements such as insulin are essential for long-term growth of commonly used mammalian cell lines. When insulin is absent from media, cell may exhibit disturbances in morphology and growth rate. Insulin, recombinant human （rHu） is identical in function and structure to the native human sequence. A hormone consisting of two polypeptide chains, rHu Insulin′s A-chain （21 amino acids） and B-chain （30 amino acids） are covalently linked by disulfide bonds between cysteine residues. This genetically engineered human insulin is a full sequence molecule producted by recombinant DNA technology in baker′s yeast.

Biochem/physiol Actions
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

个人防护装备 Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK德国 nwg
RTECS NM8900250