北京现货 Peprotech 200-13 Recombinant Human IL-13

北京现货 Peprotech 200-13 Recombinant Human IL-13       北京杰辉生物技术有限公司对外承揽试验：免疫组化,荧光，Tunel，Elisa，WB，原位杂交，比色法，HE染色,特染,图像分析，欢迎咨询！（北京杰辉生物技术有限公司）北京杰辉生物技术有限公司免费代测ELISA试剂盒一周内出结果
北京现货 Peprotech 200-13 Recombinant Human IL-13Catalog Number:
200-13
Synonyms:
NC30 (Human), P600 (Murine)
Description:
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells.  Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites.  IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8.  IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE.  Blocking of IL-13 activity inhibits the pathophysiology of asthma.  Human and murine IL-13 is cross-species reactive.  Recombinant human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.
AA Sequence:
MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Cross Reactivity:
Mouse, Human, Bacteria, Leech, Mon
key, Pig