磷酸化系统性红斑狼疮先关蛋白TREX1抗体,Anti-phospho-ATRIP(Ser68+Ser72)抗体

“磷酸化系统性红斑狼疮先关蛋白TREX1抗体,Anti-phospho-ATRIP(Ser68+Ser72)抗体高兴而来   ”我公司拥有领先的细胞服务技术，先进的设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等，广泛用于多种分析研究与技术测定。欢迎来电咨询，我们将竭诚为你服务！
产品编号：byk-11224R    
产品规格：0.1ml/0.2ml
产品用途：科研实验
产品介绍：
DNA damage or incomplete replication of DNA results in the inhibition of cell cycle progression at the G1 to S or the G2 to M phase transition by conserved regulatory mechanisms known as cell cycle checkpoints. Checkpoint proteins include Rad17, which is involved in regulating cell cycle progression at the G1 checkpoint as well as Chk1, Chk2, Rad1, Rad9 and Hus1, which are involved in regulating cell cycle arrest at the G2 checkpoint. In response to DNA damage, ATM and ATR kinases are important for cell cycle checkpoint response signalling. ATR-interacting protein (ATRIP), also designated ATM and Rad3-related-interacting protein, is required for checkpoint signaling after DNA damage. It is also important for ATR expression, which regulates DNA replication and damage checkpoint responses. ATRIP is a ubiquitously expressed protein that can form heterodimers with ATR. After dimerization they bind the RPA complex and are recruited to single stranded DNA. ATRIP is a nuclear protein that may also play a role in protein stabilization.
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