Ceftibuten/头孢布坦
产品编号:C069
产品规格:10mg/50mg/100mg
CAS Number | 97519-39-6 |
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Molecular Formula |
C15H14N4O6S2 |
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Molecular Weight | 410.42 g/mol |
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Form | Powder |
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Appearance | White to tan powder |
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Purity Level | ≥95.0% |
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Solubility | DMSO |
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Source | Synthetic |
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Boiling Point | 966.4 °C |
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Flash Point | 538.3 °C |
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Storage Conditions | 2-8 °C |
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Description
Ceftibuten is a third generation cephalosporin antibiotic. Ceftibuten is freely soluble in aqueous solution (70.5 mg/mL).
Mechanism
like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.
Spectrum
Ceftibuten is a broad spectrum antibiotic targeting a wide variety of gram positive and gram negative bacteria.
Microbiology Applications