S035 Sulfadoxine (Sulphadoxine)/磺胺多辛

Sulfadoxine (Sulphadoxine)/磺胺多辛
产品编号：S035 
产品规格：10g/25g

CAS Number	2447-57-6
Molecular Formula	C12H14N4O4S
Molecular Weight	310.33 g/mol
Form	Powder
Purity Level	99.0-101.0%
Solubility	Water: 0.296 mg/mL (predicted)
Melting Point	197 °C
Storage Conditions	-20 °C

Description
Sulfadoxine is a sulfonamide antibiotic frequently used for the treatment of malaria and bacteria that cause urinary and respiratory tract infections.  Sulfadoxine is also routinely used in combination for malaria infections when used in combination with pyrimethamine. Sulfadoxine is soluble in water and ethanol: 0.296 mg/mL and 20mg/mL respectively.
Mechanism
like most sulfonamides, sulfadoxine inhibits folic acid synthesis by acting as a competitive inhibitor of dihydropteroate synthetase, an enzyme found in the folic acid synthesis pathway.
Spectrum
Sulfadoxine is a broad spectrum antibiotic targeting a wide range of Gram-positive and Gram-negative bacteria.