Salinomycin sodium/盐霉素
产品编号:S002
产品规格:1g
CAS Number | 55721-31-8 |
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Molecular Formula | C42H69NaO11 · x H2O |
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Molecular Weight | 772.98 g/mol (anhydrous basis) |
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Form | Powder |
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Appearance | White crystalline powder |
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Purity Level | ≥90.0% |
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Solubility | Water: Soluble |
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Source | Streptomyces Albus |
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pH | 6.5-8.5 |
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Melting Point | 140-142 °C |
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Storage Conditions | 2-8 °C |
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Description
Salinomycin is a coccidiostat ionophore antibiotic.
TOKU-E offers two forms of salinomycin: salinomycin (S001) and salinomycin sodium (S002). Salinomycin is slightly soluble in methanol at 10 mg/mL. Salinomycin sodium is freely soluble in water.
Mechanism
Salinomycin interacts with the gram positive cell membrane which decreases control of ion permeability. This effect allows ions (K+, Na+, Ca+, Mg2+) to accumulate inside the cell to toxic levels.
Spectrum
Salinomycin targets primarily the gram positive cell wall to allow ion transport into the cell. Gram negative organisms are unaffected by salinomycin because of their additional outer membrane.
Microbiology Applications
Salinomycin is commonly used in clinical in vitro microbiological antimicro