Nitrofurantoin/呋喃咀啶
产品编号:N006
产品规格:10g/100g/250g
CAS Number | 67-20-9 |
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Molecular Formula | C8H6N4O5 |
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Molecular Weight | 238.16 g/mol |
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Form | Powder |
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Appearance | Yellow crystalline powder |
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Purity Level | 98.0-102.0% |
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Solubility | Water: 79.5 μg/mL
Dimethaylformamide: Soluble |
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Source | Synthetic |
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Water Content (Karl Fisher) | <1.0% |
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Melting Point | 270-272 °C |
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Storage Conditions | Store protected from light, at a temperature below 25 C. NOTE: Nitrofurantoin and solutions of it are discolored by alkali and by exposure to light, and are decomposed upon contact with metals other than stainless steel and aluminum. |
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Description
Nitrofurantoin is a unique bacteriostatic antibiotic. Nitrofurantoin is sparingly soluble in aqueous solution at 0.0795 mg/mL; however, it is highly soluble in DMF at 80 mg/mL.
Mechanism
Upon entering a susceptible cell, nitrofurantoin is activated by bacterial enzymes and targets ribosomes and nucleic acids which inhibit bacterial growth.
Spectrum
Nitrofurantoin is a broad spectrum antibiotic commonly targeting bacteria responsible for causing urinary tract infections.
Microbiology Applications