活化转录因子1抗体,Anti-ATF1抗体

抗体（antibody）指机体的免疫系统在抗原刺激下，由B淋巴细胞或记忆细胞增殖分化成的浆细胞所产生的、可与相应抗原发生特异性结合的免疫球蛋白。主要分布在血清中，也分布于组织液及外分泌液中。
活化转录因子1抗体,Anti-ATF1抗体实验专用产品信息：
中文名称：活化转录因子1抗体   
英文名称：Anti-ATF1
产品编号：byk-0517R
产品规格：0.1ml/0.2ml  
产品用途：科研实验
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活化转录因子1抗体,Anti-ATF1抗体实验专用介绍：
ATF1 (Activating Transcription Factor 1, TREB-36) is a member of the ATF/CREB family of basic region leucine-zipper (bZip) DNA-binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. The activation function of CRE-binding proteins may be modulated by phosphorylation of several kinases and is mediated by coactivators such as CREB-binding protein (CBP) and p300. ATF1 is a nuclear protein that binds DNA as a homodimer or as heterodimers with the inducible transcription factors CREB1 or CREM. Heterodimers appear to be stronger transcriptional activators than the homodimers. Tissue expression of ATF1 mRNA is widespread. Several isoforms of ATF1 arise by differential splicing. ATF1 mediates both Ca2+ and cAMP responses at several levels. It binds to the Tax-responsive element (TRE1) of the human T-cell lymphotropic virus type-I (HTLV1). ATF1 is detectable in metastatic melanoma cells and seems to contribute to their survival. A chimeric protein composed of the N-terminal domain of EWS (Ewing sarcoma oncogene) linked to the bZip domain of ATF1 is implicated in the rare malignant clear cell sarcoma of tendon sheath and aponeuroses  
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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Anti-Defensin β1(mouse rat)  防御素β1抗体(小鼠、大鼠)
Anti-Defensin β1(human)  防御素β1抗体(人)
Anti-DEK oncogene (DNA binding)  DEK癌基因结合蛋白
Anti-Defensin β2/beta-defensin 2/BD-2（to mouse）  防御素β2抗体（小鼠）
Anti-Defensin β2/beta-defensin 2/BD-2（to rat）  防御素β2抗体（大鼠）
Anti-DAP-5/p97 (Death Associated Protein-5)  死亡相关蛋白5抗体
Anti-DAPK1（Death associated protein kinase 1）  凋亡相关蛋白激酶1抗体
Anti-DAPK2（Death associated protein kinase 2）  凋亡相关蛋白激酶2抗体
Anti-DAPK3（Death associated protein kinase 3）  凋亡相关蛋白激酶3抗体
Anti-Deltex-1  DTX1 (Deltex protein 1)