Asc-576 Asenapine maleate

Asenapine maleate
产品编号：Asc-576 
产品规格：10mg/50mg
Product name
Asenapine maleate
Description
Multiple receptor antagonist. Anti-psychotic agent.alternative namesASE
Biological description
Novel, multiple receptor antagonist. Displays activity at 5-HT, dopamine, adrenoceptors and histamine receptors. (pKi values are 8.60 (5-HT1A), 8.40 (5-HT1B), 10.15 (5-HT2A), 9.75 (5-HT2B), 10.46 (5-HT2C), 8.84 (5-HT), 9.60 (5-HT6), 9.94 (5-HT7), 8.85 (D1), 8.90 (D2L), 8.84 (D2S), 9.38 (D3), 8.95 (D4), 8.93 (a1A), 8.9 (a2A), 9.49 (a2B), 8.91 (a2C), 9.00 (H1) and 8.21(H2) receptors respectively). Increases dopamine, norepinephrine and acetylcholine efflux. Anti-psychotic in vivo.Purity
> 99%General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.Properties
Chemical name
trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole maleateMolecular Weight
401.85Chemical structure
Molecular formula
C17H16ClNO.C4H4O4CAS Number
85650-56-2Solubility
Soluble in DMSO to 100 mM and in ethanol to 100 mMStorage instructions
Store at +4°C.