BIA-A1010 Avermectin B1a/阿维菌素B1a

Avermectin B1a/阿维菌素B1a
产品编号：BIA-A1010 
产品规格：1 mg/5 mg 
Avermectin B1a is the major component (>80%) of the
commercially available anthelmintic Abamectin? used to control
parasitic nematodes in livestock. Avermectin B1a contains a secbutyl
residue in the 25-position. In vitro and in vivo studies have
shown this analogue is the more potent analogue in the
commercial product.
CAS Number: 65195-55-3
Molecular Formula: C48H72O14
Molecular Weight: 873.1
Source: from Streptomyces avermitilis
Purity: >99% by HPLC
Long Term Storage : -20°C
Solubility : Soluble in ethanol, methanol, DMF or DMSO.
References
1. Avermectin B1a irreversibly blocks postsynaptic potentials at the lobster neuromuscular junction by
reducing muscle membrane resistance. Fritz L.C. et al. Proc. Natl Acad. Sci. USA 1979, 76, 2062.
2. Solubilization and characterization of a high affinity ivermectin binding site from Caenorhabditis elegans.
Cully D.F. et al. Mol Pharmacol. 1991, 40, 326.
3. Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics.
Wolstenholme A.J. & Rogers A.T. Parasitology 2005, 131, S85-95.
阿维菌素 B1a（Avermectin B1a）
货号： BIA-A1010 包装规格: 1 mg, 5 mg
阿维菌素 B1a 是商业化的家畜寄生性线虫驱虫剂 Abamectin? 的主要成分 （>80%）。 阿维菌素 B1a在25位上含有仲丁基残基。体内与体外研究均表明阿维菌素B1a 是商品中含有的同类物中比较有效的一种
CAS号: 65195-55-3
分子式: C48H72O14
分子量: 873.1
来源: 来自于链霉菌属avermitilis
纯度: >99% by HPLC