K013 Kanamycin A sulfate, EvoPure/硫酸卡那霉素A, EvoPure

Kanamycin A sulfate, EvoPure/硫酸卡那霉素A, EvoPure
产品编号：K013 
产品规格：100mg

CAS Number	25389-94-0
Molecular Formula	C18H36N4O11·H2SO4
Molecular Weight	582.58 g/mol
Form	Powder
Appearance	White powder
Purity Level	≥99.0%
Solubility	Freely soluble
Source	Streptomyces Kanamyceticus
Boiling Point	943.2 °C
Melting Point	250 °C
Flash Point	524.2 °C
Storage Conditions	2-8 °C

Description
Kanamycin is an aminoglycoside antibiotic often used to select for plants (Agrobacterium mediated transformation) and bacteria which have been successfully transformed with a plasmid conferring kanamycin resistance.  Kanamycin is very soluble in aqueous solution at 92.3 mg/mL.
Standard grade kanamycin is composed of a mixture of three different fractions: kanamycin A, B, and C. TOKU-E offers five forms of kanamycin: kanamycin sulfate (K008), kanamycin disulfate (K004), kanamycin A sulfate, EvoPure? (K013), kanamycin B sulfate (K002), and kanamycin B sulfate, EvoPure? (K014).  EvoPure? products are purified single antibiotic fractions, most >99% pure. High purity EvoPure? kanamycin products can be used to analyze the specific effects of individual kanamycin fractions.
Mechanism
Aminoglycosides target the 30S ribosomal subunit resulting in an inability to read mRNA ultimately producing a faulty or nonexistent protein.
Spectrum
Kanamycin is a broad spectrum antibiotic, however, it is mostly used against aerobic gram negative bacteria.
Microbiology Applications
Kanamycin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram positive and gram negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients. Representative MIC values include:Salmonella enteritidis 62.5 μg/mL
Escherichia coli 31.2 μg/mL
For a complete list of kanamycin MIC values, click here.Media Supplements
Kanamycin can be used as a selective agent in several types of isolation media:
Kanamycin Aesculin Azide Agar - Enterococci isolation in food
Plant Biology Applications