H010 Hygromycin B, EvoPure/潮霉素B, EvoPure

Hygromycin B, EvoPure/潮霉素B, EvoPure
产品编号：H010 
产品规格：1g/10g/5x10g

CAS Number	31282-04-9
Molecular Formula	C20H37N3O13
Molecular Weight	527.52 g/mol
Form	Powder
Appearance	Off-white to tan powder
Purity Level	≥99.5%
Solubility	Freely soluble
Source	Streptomyces Hygroscopicus
Boiling Point	897.6 °C
Melting Point	160-180 °C
Flash Point	496.7 °C
Storage Conditions	2-8 °C

Description
Hygromycin B is an aminoglycoside antibiotic which targets both prokaryotic and eukaryotic cells.
TOKU-E offers five forms of hygromycin B: hygromycin B (H007), hygromycin B, EvoPure? (H010), hygromycin B solution (H011), hygromycin B, EvoPure? solution (H015), and hygromycin B, concentrated solution (H001).
Hygromycin B (H007) and hygromycin B, EvoPure? (H010) are both freely soluble in aqueous solution. Hygromycin B solution (H011) is prepared at 50 mg/mL in PBS buffer. Hygromycin B, EvoPure? solution (H015) is prepared at 100 mg/mL. Hygromycin B, concentrated solution (H001) is prepared at 450,000 U/mL. EvoPure? products are purified single antibiotic fractions, most >99% pure.
Mechanism
Toxicity of hygromycin B is thought to arise from inhibiting protein synthesis by strengthening the interaction of peptidyl-tRNA in the ribosomal acceptor ("A") site preventing translocation by EF-2 (elongation factor 2).
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