LL-37, acetylated, amidated 是一种 N 末端乙酰化,C 末端酰胺化的组织蛋白酶肽 LL-37。人组织蛋白酶肽 LL-37 对多种革兰氏阳性和革兰氏阴性人体病原体具有KJ和抗生物膜活性,对宿主有伤口愈合作用。
Description LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. The single human cathelicidin peptide LL-37 has antimicrobial and anti-biofilm activity against multiple Gram-positive and Gram-negative human pathogens, and has wound-healing effects on the host[1].
Molecular Weight 4534.40
Formula C₂₀₇H₃₄₃N₆₁O₅₃
Sequence Ac-{Leu}{Leu}{Gly}{Asp}{Phe}{Phe}{Arg}{Lys}{Ser}{Lys}{Glu}{Lys}{Ile}{Gly}{Lys}{Glu}{Phe}{Lys}{Arg}{Ile}{Val}{Gln}{Arg}{Ile}{Lys}{Asp}{Phe}{Leu}{Arg}{Asn}{Leu}{Val}{Pro}{Arg}{Thr}{Glu}{Ser}-NH2
Sequence Shortening Ac-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-NH2
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献:
[1]. Duplantier AJ, et al. The Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for PolymicrobialInfected Wounds. Front Immunol. 2013 Jul 3;4:143.
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