14-3-3σ抗体,Anti-14-3-3 sigma抗体

“14-3-3σ抗体,Anti-14-3-3 sigma抗体 ”我公司拥有领先的细胞服务技术，先进的设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等，广泛用于多种分析研究与技术测定。欢迎来电咨询，我们将竭诚为你服务！
抗体（antibody）指机体的免疫系统在抗原刺激下，由B淋巴细胞或记忆细胞增殖分化成的浆细胞所产生的、可与相应抗原发生特异性结合的免疫球蛋白。主要分布在血清中，也分布于组织液及外分泌液中。
产品规格：0.1ml/0.2ml
中文名称：14-3-3σ抗体    
英文名称：Anti-14-3-3 sigma 
产品编号：byk-12422R  
产品用途：科研实验
性 状： Lyophilized or Liquid
浓 度： 1mg/1ml
亚 型： IgG
贮 存： 贮存于-20℃.
相关标记: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
14-3-3σ抗体,Anti-14-3-3 sigma抗体 相关产品：
Anti-G Protein(Guanine nucleotide-binding regulatory protein)beta polypeptide 1  G蛋白/鸟苷酸结合蛋白抗体
Anti-GABRA1(gamma-aminobutyric acid (GABA) A receptor, alpha 1)  γ1氨基丁酸A型受体α1抗体
Anti-GABRB1(GABA B Receptor 1)  γ1氨基丁酸A型受体B1抗体
Anti-GABABR2/GB2(GABA B Receptor 2)  γ1氨基丁酸A型受体B2抗体
Anti-GAD-65 (glutamate decarboxylase)  谷氨酸脱羧酶-65抗体
Anti-GAD-67 (glutamate decarboxylase 67)  谷氨酸脱羧酶-67抗体
Anti-GAD-65 (glutamate decarboxylase)  谷氨酸脱羧酶-65抗体(C端多肽)
Anti-GADD34/PPP1R1(Growth arrest and DNA damage-inducible 34)  生长YZDNA损伤基因34抗体
Anti-GADD45(Growth arrest and DNA damage-inducible 45)  生长YZDNA损伤基因45抗体
Anti-GADD153/CHOP(Growth arrest and DNA damage-inducible 153)  生长YZDNA损伤基因153(CCAAT增强子结合蛋白同源蛋白)抗体
14-3-3σ抗体,Anti-14-3-3 sigma抗体 产品详情：
14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms, denoted 14-3-3 b, g, e, z, h, q and s, comprise this family of signaling intermediates. 14-3-3 s, also known as SFN, stratifin, HME1 or YWHAS, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways. Expressed predominately in stratified squamous keratinising epithelium, 14-3-3 s is able to bind and modify the activity of a large number of proteins, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif. When bound to Keratin 17, for example, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth. 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, thus controlling mitotic translation. In response to tumor growth, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression. Multiple isoforms of 14-3-3 s exist due to alternative splicing events.