“磷酸化相关死亡促进因子抗体,Anti-BAD (Ser128)抗体 ”我公司拥有领先的细胞服务技术,先进的设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等,广泛用于多种分析研究与技术测定。欢迎来电咨询,我们将竭诚为你服务!
抗体(antibody)指机体的免疫系统在抗原刺激下,由B淋巴细胞或记忆细胞增殖分化成的浆细胞所产生的、可与相应抗原发生特异性结合的免疫球蛋白。主要分布在血清中,也分布于组织液及外分泌液中。
产品规格:0.1ml/0.2ml
中文名称:磷酸化相关死亡促进因子抗体
英文名称:Anti-phospho-BAD (Ser128)
产品编号:byk-0893R
产品用途:科研实验
性 状: Lyophilized or Liquid
浓 度: 1mg/1ml
亚 型: IgG
贮 存: 贮存于-20℃.
相关标记: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
磷酸化相关死亡促进因子抗体,Anti-BAD (Ser128)抗体 相关产品:
Anti-CXCL9/MIG/CMK γ干扰素诱导单核细胞因子抗体
Anti-CXCL11/ITAC/SCYB11 干扰素诱导T细胞趋化因子抗体
Anti-CXCL13/BLC-1(C-X-C motif chemokine 13) B-淋巴细胞趋化因子抗体
Anti-CXCL15/Lungkine 趋化因子CXCL15体
Anti-GCK/GLK(Glucokinase) 抗葡萄糖激酶抗体
Anti-GCS(glucosylceramide synthase) 谷氨酸半胱氨酸γ合成酶抗体
Anti-G-CSF/CSF3(Granulocyte Colony Stimulating Factors 3) 粒细胞-巨噬细胞集落刺激因子 3抗体
Anti-G-CSFR/CSF3R/CD114(Granulocyte colony-stimulating factor receptor precursor) 粒细胞-巨噬细胞集落刺激因子3受体抗体
Anti-GDF-1(growth differntiation factor 1) 抗生长、分化因子1抗体
Anti-GDF8/MSTN(growth differntiation factor 8) 生长分化因子8抗体
磷酸化相关死亡促进因子抗体,Anti-BAD (Ser128)抗体 产品详情:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.