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抗体(antibody)指机体的免疫系统在抗原刺激下,由B淋巴细胞或记忆细胞增殖分化成的浆细胞所产生的、可与相应抗原发生特异性结合的免疫球蛋白。主要分布在血清中,也分布于组织液及外分泌液中。
产品规格:0.1ml/0.2ml
中文名称:细胞质分裂付出蛋白2抗体
英文名称:Anti-DOCK2
产品编号:byk-12431R
产品用途:科研实验
性 状: Lyophilized or Liquid
浓 度: 1mg/1ml
亚 型: IgG
贮 存: 贮存于-20℃.
相关标记: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
T细胞质分裂付出蛋白2抗体,Anti-DOCK2抗体 相关产品:
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Anti-GLUT1(Glucose transporter type 1) 葡萄糖转运蛋白1抗体
Anti-GLUT2(Glucose transporter type 2) 葡萄糖转运蛋白2抗体
Anti-GLUT3(Glucose transporter 3) 葡萄糖转运蛋白3抗体
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Anti-GlyR alpha 1/2/3(Glycine receptor alpha 1/2/3) 甘氨酸受体alpha 1/2/3型抗体
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T细胞质分裂付出蛋白2抗体,Anti-DOCK2抗体 产品详情:
The DOCK2 gene encodes dedicator of cytokinesis 2 (DOCK 2), a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis. DOCK 2 participates in the cytoskeletal rearrangements that are required for lymphocyte migration in response of chemokines. This peripheral membrane protein activates Rac 1 and Rac 2 small GTPases, while presumably acting as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK 2 may also participate in IL-2 transcriptional activation through the activation of Rac 2. DOCK 2 contains one DHR-1 (CZH-1) domain, one DHR-2 (CZH-2) domain and one SH3 domain. The DHR-2 domain is a putative GEF activity mediator. The DOCK 2 protein also co-localizes with F-Actin, and demonstrates expression in several human tissues, with the highest levels observed in peripheral blood leukocytes, thymus, spleen and liver.