Streptozotocin/链脲佐菌素
产品编号:BIA-S1186
产品规格:25mg/100mg
Streptozotocin is an unusual aminoglycoside containing a
nitrosoamino group produced by Streptomyces achromogenes
discovered in 1959 as an antibiotic. The nitrosoamino group
enables the metabolite to act as a nitric oxide (NO) donor. NO is
an important messenger molecule involved in many physiological
and pathological processes in the body. Streptozotocin is also
widely used to induce diabetes in rodent models by inhibition of ?-
cell O-GlcNAcase.
CAS Number: 18883-66-4
Molecular Formula: C8H15N3O7
Molecular Weight: 265.2
Source: from Streptomyces achromogenes
Purity: >99% by HPLC
链脲霉素(Streptozotocin)
货号:BIA-S1186 包装规格: 25 mg, 100 mg
链脲霉素于1959年发现由链霉菌属产生的抗生素,是一种独特的包含亚硝氨基的氨基糖甙。亚硝氨基使这种代谢物充当NO的贡献者。NO在体内是一个重要的信使分子与许多生理和病理过程有关。链脲霉素还广泛应用于啮齿类动物模型中,通过YZ?细胞的脱糖基化酶 O-GlcNAcase诱导糖尿病的产生。
CAS号: 18883-66-4
分子式: C8H15N3O7
分子量: 265.2
来源:来自于链霉菌属
纯度: >99% by HPLC