BIA-M1219 Myriocin/嗜热菌杀酵母素

Myriocin/嗜热菌杀酵母素
产品编号：BIA-M1219 
产品规格：2.5mg/10mg 
Myriocin   CAS Number. 35891-70-4
  alternate Name(s):  Thermozymocidin, ISP 1  
Myriocin is an alpha-amino fatty acid derived from species of several genera of fungi, notably Myriococcum, Melanconis and Isaria. Myriocin is a potent inhibitor of sphingosine biosynthesis by blocking the first enzyme in the pathway, serine palmitoyltransferase. Myriocin induces apoptosis by depletion   of cellular sphingolipids, inhibits proliferation of IL-2-dependent mouse cytotoxic cells and is a potent immunosuppressant.
嗜热菌杀酵母素     CAS 号. 35891-70-4
别名：多球壳菌素, ISP 1 
嗜热菌杀酵母素是一种α氨基脂肪酸，从Myriococcum, Melanconis 和棒束孢属等若干种真菌中分离。嗜热菌杀酵母素是一种有效的鞘氨醇生物合成YZ剂，能阻止合成途径中一个酶——丝氨酸软脂酰转移酶。嗜热菌杀酵母素通过耗尽细胞的鞘脂类诱导凋亡，YZ白介素2依赖性的小鼠毒性细胞的增殖，是一种有效的免疫YZ剂。