BIA-F1259 Fusidate sodium/夫西地酸钠

Fusidate sodium/夫西地酸钠
产品编号：BIA-F1259 
产品规格：25 mg/100 mg
Synonyms : Fusidic acid = Fusidin, Ramycin, NSC 56192, SQ 16603, Antibiotic SQ 16603
Specifications
CAS # : 751-94-0
Molecular Formula : C31H47NaO6
Molecular Weight : 538.7
Source : Fusidium coccineum
Appearance : White to off white powder
Purity : > 98% by HPLC
Storage : -20°C
Solubility : Soluble in water, ethanol, methanol, DMF or DMSO.
Application Notes
Sodium fusidate is the more water soluble sodium salt of fusidic acid, a steriodal metabolite of Fusidium
coccineum which is a Gram +ve antibiotic. Fusidic acid inhibits protein synthesis in prokaryotes by inhibiting
the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Fusidic acid has also been
shown to suppress nitric oxide lysis of pancreatic islet cells.
References
1. Fusidic acid: a new antibiotic. Godtfredson W. O. et al. Nature 1962, 193, 987.
2. On the mode of action of fusidic acid. Harvey C. L. et al. Biochemistry 1969, 5, 3320.
3. Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics. Tanaka N. et al. BBRC
1968, 30, 278.
4. Fusidic acid suppresses nitric oxide toxicity in pancreatic islet cells. Burkart V. et al. Biochem. Pharmacol.
1994, 48, 1379.
Fusidate sodium/夫西地酸钠
货号：BIA-F1259   包装规格: 25 mg, 100 mg
同义词：Fusidic acid = Fusidin, Ramycin, NSC 56192, SQ 16603, Antibiotic SQ 16603
CAS号: 751-94-0
分子式: C31H47NaO6
分子量: 538.7
来源: 来自于Fusidium coccineum
纯度: > 98% by HPLC