N-tetradecanoyl-L-Homoserine lactone

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产品名称：N-tetradecanoyl-L-Homoserine lactone

产品别名：C₁₄-HSL;tDHL;

CAS号：202284-87-5

英文别名：N-tetradecanoyl-L-Homoserine lactone

分子量：311.5

分子式：C₁₈H₃₃NO₃

纯度：≥98%

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保存方法：Store at -20℃

描述：Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxR family of proteins, is coordinated by the synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-tetradecanoyl-L-Homoserine lactone (C₁₄-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria.^1,2,3 It appears later than shorter acyl chain AHLs in developing biofilms⁴ and, like other long chain AHLs, stimulates bacterial growth.⁵ C₁₄-HSL also alters the proteolytic activity and enhances the migration of some strains of Proteus mirabilis.⁶

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